Pulmonary artery hypertension (PH), associated with increased left ventricular (LV) diastolic pressure and pulmonary vasoconstriction, is frequently observed in heart failure (HF), where it holds prognostic significance. We hypothesized that Cheyne-Stokes respiration (CSR) may contribute to increased pulmonary arterartery pressure (PAP) and right ventricular (RV) remodeling in HF, via hypoxia/hypercapnia cycles and adrenergic activation by the chemoreflex stimulation.

Influence of central apneas and chemoreflex activation on pulmonary artery pressure in chronic heart failure

Giannoni, Alberto;DEL FRANCO, ANNAMARIA;AIMO, ALBERTO;EMDIN, MICHELE;PASSINO, Claudio;MIRIZZI, GIANLUCA
2016-01-01

Abstract

Pulmonary artery hypertension (PH), associated with increased left ventricular (LV) diastolic pressure and pulmonary vasoconstriction, is frequently observed in heart failure (HF), where it holds prognostic significance. We hypothesized that Cheyne-Stokes respiration (CSR) may contribute to increased pulmonary arterartery pressure (PAP) and right ventricular (RV) remodeling in HF, via hypoxia/hypercapnia cycles and adrenergic activation by the chemoreflex stimulation.
2016
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11382/502879
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